What are Neuromodulators?

More popularly known by their branded names, Botox and Dysport, neuromodulators are a very popular way to address forehead and brow wrinkling created by repetitive movements or that form when making certain facial expressions. Neuromodulators relax the treated muscles and therefore reduce the appearance of wrinkles.

This minimally invasive treatment continues to grow in popularity with patients looking to use it both preventively and for existing wrinkles.

What are My Neuromodulator Options?

Any FDA-approved neuromodulator option must be comprised of a safe dosage of botulinum toxin and each type is used for relaxing muscles by blocking nerve signals from reaching the facial muscles in the area of injection. By dampening the muscle response, the skin above the muscles isn’t stretched and creased as dramatically, which can leave behind fine lines and wrinkles over time. This means not only does Botox and its relatives improve the current signs of wrinkles, but can also help prevent their early appearance when beginning Botox injections at the first sign of creasing.

Your options aren’t limited to just Botox at CosmedicDerm. Depending on your unique experience with dynamic wrinkles, we can offer you any of the following formulas:

  • Botox®

  • Dysport®

  • Xeomin®

  • Jeuveau®

Botox vs. Dysport

While these brands use the same basic active ingredient to treat facial wrinkles, their main differences exists on the molecular level. Dysport has smaller molecules and is injected deeper, which allows it to take effect quicker than Xeomin and Botox. However, with smaller molecules, this allows the product to spread more, making it less targeted.

Botox and Xeomin have larger molecules and are not injected as deeply as Dysport. This means that the molecules don’t have much movement, resulting in a more targeted treatment that’s ideal for areas like near the eyes that are sensitive.

Xeomin is the latest product and has no attached proteins to the active ingredient. Taking these factors into account is important when choosing a product to address your skin concerns.


Xeomin contains just one ingredient — botulinum toxin A— without any additives, making it the most purified product. Of the three neuromodulators, it’s the only one that does not require refrigeration due to the lack of additives in it. Manufactured by Merz Pharmaceuticals, Xeomin is approved by the FDA for the treatment of blepharospasm and cervical dystonia in adults, as well as the elimination of moderate to severe frown lines between the eyebrows.

The effects of Xeomin can usually be seen within 5 days. Most people see improvement in their forehead lines as soon as the next day after their treatment. However, the final results are visible in up to 10 days. The effects of Xeomin also last a couple weeks longer than your Botox results, on average. Since Xeomin is a purified product, you are less likely to become resistant to it.


Jeuveau, sometimes called Newtox, is the newest injectable neuromodulator available. It’s made with botulinumtoxin type A similar to Botox, Dysport, and Xeomin, but Jeuveau is the only neuromodulator specifically FDA-approved for cosmetic use. Since Jeuveau was developed specifically as a cosmetic treatment (rather than a medical treatment like Botox) it has a variety of benefits, including lower cost and more effective cosmetic results.

Jeuveau can reduce the appearance of fine lines and wrinkles in the upper face, including brow lines, frown lines, and crow’s feet. It can produce results in 1-2 weeks and can last for 3-6 months – it’s also interchangeable with other neuromodulator treatments so you can explore your options with Jeuveau even if you already use Botox or another injectable treatment.

What Skin Concerns Can Neuromodulators Treat?

  • Fine lines and wrinkles: crow’s feet, laugh lines, frown lines, forehead lines, etc.

  • Facial asymmetry

  • Muscle spasms

  • Chronic migraines

  • Excessive sweating

  • Crossed or lazy eyes

The original development of these formulas was for medical purposes, but the benefits of neuromodulators has spread into the cosmetic space, helping people achieve a youthful appearance for longer with simple Botox treatments performed regularly.

Downtime & Side Effects after Botox Treatment

There is no downtime after Botox, Dysport, or Xeomin treatments. The most common side effect is the skin becoming raised and slightly red at the injection site. This will subside within a few hours and should not be terribly noticeable. Sensitivity will be increased, so you should protect your skin from too much sun exposure in addition to avoiding strenuous exercise. You should avoid rubbing or manipulating the areas for the next 24 hours for the best results.

On average, the effects from either product should last anywhere from three to six months.

Schedule a Consultation about Botox Near Detroit

If you are interested in learning more about your neuromodulator options and if they are right for you, call the CosmedicDerm office today to schedule a consultation. Dr. Shauna Diggs and her staff are ready to offer you best-in-class medical and cosmetic care as Michigan’s leaders in comprehensive skin health and rejuvenation. These days, your options aren’t just limited to Botox Cosmetic, which is why people choose CosmedicDerm for the most personalized suggestions and the latest techniques and formulas for the best-looking complexion of their life.